The Pharma Test / Pharmag YM-4 V-Blender Attachment (part number: 40-01150) is designed for pharmaceutical formulation development (R&D), Galenical Labs, and small-scale pilot-scale processes. This module requires a P-UGD universal gearbox for seamless connection with the P-UAM universal motor drive unit. It is specifically designed for highly uniform convection mixing of dry powders and granules, and is particularly suitable for high-dilution ratios (micro-APIs) and shear-sensitive powder formulations. It fully complies with the stringent requirements of cGMP, GLP, FDA, and the International Pharmacopoeia.

I. Utilizing the V-shaped "pant-leg region" geometry, a triple composite motion of dividing, cascading, and intermeshing is continuously generated during horizontal rotation. The material periodically tumbles and reassembles at the apex and both arms, completely eliminating mixing dead zones and stratification segregation.

II. Designed for ultra-uniform dispersion of trace active ingredients (APIs) and base excipients, with a mixing dilution ratio as low as 1%, achieving extremely high batch mixing uniformity and reproducibility in a short time.

III. The mixing process does not generate excessive frictional heat or high mechanical shear force, thus fully protecting sensitive powders, fragile particles, pellets, and specific crystal structures.

IV. Quickly connect to the P-UAM universal motor drive unit via the standard P-UGD universal gearbox. The unit provides precise stepless speed adjustment over a wide range of 5-45 rpm, ensuring smooth and stable operation and significantly saving laboratory workspace and equipment purchase costs.

V. Widely applicable to a variety of industries including pharmaceuticals, traditional Chinese medicine/alternative therapies, fine chemicals, food and agriculture, cement and ceramics, cosmetics, detergents, and paints and pigments.

VI. All material contact parts of the machine are made of pharmaceutical and food-grade corrosion-resistant stainless steel with a smooth surface and no dead corners, supporting the sterilization and cleaning validity standards that meet GMP specifications.

Equipment Introduction

• 3D Blending & Multi-Directional Tumbling Mechanism

  • Triple three-dimensional flow characteristics (Dividing, Cascading and Intermeshing) : The material is placed in a symmetrical V-shaped "pant-leg region" geometric cavity. As it rotates smoothly along the horizontal axis, the material periodically shuttles back and forth between the apex and the two side arms, continuously performing dividing, gravity cascading, and intermeshing, completely eliminating mixing dead zones and powder segregation.

  • High Dilution Capacity & Micro-Dosing : Designed for ultra-uniform dispersion of trace active ingredients (APIs) and base excipients, with a minimum dilution ratio of 1% (Highly Diluted Powder Blends) , achieving extremely high content uniformity and batch reproducibility in a short time.

• Low-Shear Gentle Processing for Sensitive Materials

  • Gentle Tumbling Action : Compared to forced mechanical shear blades, V-shaped natural tumbling mixing does not generate additional frictional heat and destructive shear force, and can completely protect brittle particles, pellets, special crystal structures and coatings.

  • Blending of Dry Powders (Solid / Solid) : A highly efficient premixing and homogenization process specifically designed for various dry powders, pellets, granulated particles, and fine crystals.

• Modular Universal Drive & Precision Speed Control

  • Seamless P-UGD/P-UAM Compatibility : This module requires a standard P-UGD universal gearbox, powered by a P-UAM universal motor drive unit, enabling tool-free installation and removal via a universal quick-release interface.

  • Precision continuously variable speed regulation (5 – 45 rpm) : Supports fine-tuning of the speed from 5 to 45 rpm by the main unit, allowing the operator to precisely set the optimal tumbling speed according to powder flowability, filling rate and process requirements.

• Optimized 4.5L Capacity & Scale-up for Laboratory Capacity and Pilot Process Integration

  • 4.5 L Total Capacity / Up to 3.0 L Operating Volume :

    • Total Capacity: 4.5 L.

    • Operating capacity: Up to 3.0 L (actual capacity depends on the characteristics of the feed material and process parameters).

  • Ideal for research and development and pilot-scale production : prescription screening and hybrid parameter optimization can be performed in very small batches, the data is highly reproducible, and it is convenient for parameter scale-up and transfer in subsequent mass production processes.

• Highly corrosion-resistant sanitary structure and effective compliance design (Sanitary Stainless Steel & GMP Compliance)

  • Pharmaceutical-grade corrosion-resistant stainless steel parts throughout : All parts in contact with materials are made of high-quality corrosion-resistant stainless steel with a smooth and easy-to-clean surface, and are resistant to various organic solvents and cleaning agents.

  • Supports sterilizable and easy cleaning : The fully open structure leaves no dead corners and residues, fully complying with cGMP, GLP, FDA and International Pharmacopoeia standards for cleaning validity in laboratories and pilot processes.