Pharma Test PTG-S5 Fully Automated Powder Flowability Analyzer
The Pharma Test PTG-S5 fully automated powder and particle flow analyzer is designed for pharmaceutical formulation development, quality control (QC), and solid dosage form process control (IPC). It can be used to quickly evaluate the flowability, angle of repose, and volumetric properties of powders and particles. This instrument fully complies with international standards for powder flowability, including the United States Pharmacopeia (USP) <1174>, the European Pharmacopoeia (EP) <2.9.16/2.9.36>, the Japanese Pharmacopoeia (JP), and ISO 4324.
I. Supports five-in-one fully automatic measurement function, which can accurately measure the flow time, flow rate, angle of repose, cone volume, and density/weight of powder.
II. Equipped with a non-contact high-precision laser optical sensor, it accurately scans the geometric contour of the cone and automatically calculates the angle of repose the instant the sample stacking is completed, completely eliminating subjective human judgment errors.
III. It features a built-in high-sensitivity precision analytical balance and an adjustable frequency programmable vibration feed module, and offers a variety of interchangeable standard funnels and outlet orifices to accommodate powder samples with different flow properties.
IV. It adopts a color touch screen interface and has built-in methods storage, real-time curve chart analysis, multi-level user permission control and tamper-proof audit trail functions, fully complying with GMP and 21 CFR Part 11 data integrity regulations.
Equipment Introduction
Comprehensive 5-in-1 Automated Powder Testing
Multi-parameter flow parameter integrated measurement : A single test procedure can automatically measure flow time, flow rate, angle of repose, cone volume, and sample weight/density.
Comprehensive evaluation of flow behavior : A comprehensive assessment of the flowability, cohesiveness, and packing characteristics of powders and particles, providing key physical property data for tableting, capsule filling, and powder mixing.
Non-Contact Laser Optical Scanning System
High-precision contour laser measurement : Equipped with an advanced non-contact laser sensor, the sample is stacked into a cone and multi-point geometric contour scanning is performed instantly.
Eliminating subjective judgment errors : The microprocessor automatically calculates the angle of repose and the volume of the cone, completely eliminating the human errors of traditional visual measurement methods and manual angle measuring instruments.
High-precision analytical balance and programmating vibrator (Integrated Precision Balance & Programmating Vibrator)
Highly sensitive real-time weight sensing : The device has a built-in precision electronic analytical balance that records the sample outflow mass in real time and plots a continuous mass/time flow curve.
Adjustable frequency programmable vibration aid : Equipped with a programmable vibration feeding mechanism, it provides auxiliary feeding for powder samples with low flowability, high cohesion or easy bridging, expanding the scope of measurement applications.
Versatile Funnels & Interchangeable Nozzles (Multi-Specification Standard)
Standard replaceable funnel configuration : Offers a variety of standard stainless steel funnels in various volumes that meet the pharmacopoeia standards of different countries, are wear-resistant and easy to disassemble and clean.
Multi-diameter outlets and cylindrical nozzles : Optional outlets with different diameters such as 10 mm, 15 mm, and 25 mm, as well as cylindrical discharge kits, are available to suit different sample types such as fine powder, coarse powder, and granulated particles.
Fully compliant with Global Pharmacopeia and industrial regulations.
Fully compliant with pharmacopoeia standards of various countries : fully compliant with powder flow testing standards of the United States Pharmacopeia (USP <1174>), the European Pharmacopoeia (EP <2.9.16> / <2.9.36>), the Japanese Pharmacopoeia (JP), and the Chinese Pharmacopoeia (ChP).
Compatible with international industrial standards : It is compatible with international powder physical property evaluation standards such as ISO 4324 and DIN, and is applicable to the research and development of pharmaceuticals, cosmetics, food and chemical powders.
Intuitive Touchscreen & Real-Time Curve Analysis
Color graphical user interface : It adopts an intuitive color touch screen to display test dynamic curves, mass flow rate and cone cross-section calculation graphics in real time.
Method storage and one-click recall : Built-in large-capacity method library, which can preset various feed amplitudes, delay times and discharge conditions to achieve one-click standardized testing.
Compliance with Laws and Regulations and Data Integrity Management (Data Integrity & 21 CFR Part 11 Compliance)
Multi-level user access control : Built-in multi-level password security management and operation permission allocation strictly prevent unauthorized modification of testing methods and system parameters.
Unalterable audit trail : It has complete audit trail records, supports data export and direct printing from external printers, and fully complies with GMP, GLP and FDA 21 CFR Part 11 regulations.
Product Features
Fully automated powder flow analysis with multi-parameter repose angle.
Built-in Sartorius balance; Infrared altitude sensing
Various funnel nozzles are available as options.
Overall Specifications
Product Model : PTG-S5
Manufacturer : Pharma Test Apparatebau AG (Germany)
Version Specification : Version 1.0E
Product positioning and operating principles :
The fully automated powder and particle flow property analyzer is designed for batch-to-batch reproducibility comparison in quality control (QC), formulation development, and process scale-up design.
It integrates a high-precision infrared optical sensor with a built-in Sartorius analytical balance unit to automatically and continuously measure powder flow time, angle of repose, powder cone weight, volume, and density.
The dual infrared sensors automatically detect the start and stop timing of powder falling. After the powder flow stops, the sensor's lifting measuring arm automatically and accurately measures the height of the top of the powder cone and calculates the angle of repose in real time.
International Pharmacopoeia and regulatory compliance :
It fully complies with the European Pharmacopoeia EP <2.9.36> (angle of repose determination), EP <2.9.16> (flowability determination), the United States Pharmacopeia USP <1174>, and the International Organization for Standardization ISO 4324 (12/83).
Automatically determine the powder flow grade (e.g., excellent, good, acceptable) based on pharmacopoeia standards.
Measurement parameters and technical scope :
Angle of repose measurement range: 1.0° to 65.0°
Flowability test range: 0.1 seconds to 999 seconds (standard 100 g sample weight)
Flow time test range: 0.1 seconds to 999 seconds
Cone density measurement range: 0.000 g/ml to 6.0 g/ml
Cone weight measurement range: 1 mg to 325 g
Cone volume measurement range: 0.1 ml to 275 ml
Sample flow rate within the preset time: mg/time (provides real-time dynamic flow curves and stability charts)
Sample trough and funnel assembly :
Standard funnel capacity: approximately 450 ml (stainless steel).
Standard nozzle orifice diameter: Standard configuration includes 6, 8, 10, 15, and 25 mm. Multiple replaceable stainless steel nozzles are also available.
Nozzle adapter ring: Compatible with 4 to 10 mm dedicated adapter rings.
Sample collection tray: 100 mm diameter standard collection tray
Auxiliary mixing system: Standard configuration includes a PTG-ER electric automatic mixer (adjustable speed to overcome the feeding of highly viscous, fine powders, or easily bridging materials).
Dust prevention and operational safety :
It comes standard with a transparent anti-static dust cover, which effectively prevents dust from scattering and protects operators. It can be quickly opened or completely disassembled for cleaning.
User interface and data management :
7-inch high-resolution color LCD backlit touchscreen (can also be connected to a standard USB keyboard for data input).
Built-in firmware and database architecture compliant with US FDA 21 CFR Part 11 regulations.
Built-in complete database: supports storing test methods, user accounts, and test results.
Multi-level access control: User accounts, password complexity, password expiration time, and anti-brute-force locking features can be customized.
Complete audit tracking: Automatically records all method creation, modification, test execution, and login events, supporting quick retrieval by date.
System self-diagnostics: Built-in maintenance diagnostic menu allows for real-time monitoring of internal system temperature, power consumption of major components, and status of the built-in tilt sensor.
Report output and data transmission :
Built-in thermal printer can instantly print GMP test reports including numerical statistics, weight-time curves, flow stability graphs, and double signature fields.
It features a USB port and a LAN interface, supporting connection to external Windows printers or data transfer to external systems.
PTG-NIR near-infrared spectroscopy module (optional) :
It can be integrated with the J&M TIDAS L NIR diode array spectrometer and TIDAS DAQ3 dedicated software.
Simultaneously analyze the physical flow properties and chemiluminescence information of powder (such as moisture content, main component API concentration, spectral fingerprint identification, and mixing uniformity) in a single test cycle.
Micro-volume testing kit (optional) :
It comes with a 10 ml micro POM funnel, a dedicated micro stirring shaft, a micro sample collection tray, and a micro calibration cone, suitable for highly active or precious micro samples.
Material and structural specifications :
Airframe: Made of corrosion-resistant stainless steel that meets GLP standards.
External dimensions: Approximately 50 × 55 × 90 cm (width × depth × height)
Packaging dimensions: Approximately 90 × 67 × 80 cm (width × depth × height)
Instrument net weight / gross weight: approximately 35 kg / 50 kg
Standard Scope of Supply :
PTG-S5 test instrument main unit (built-in 7-inch touch screen, Sartorius balance unit, thermal printer)
PTG-ER Automatic Electric Mixer
Transparent antistatic dust cover
450 ml stainless steel tapered funnel
Replaceable nozzle kit (orifice diameters 6, 8, 10, 15, 25 mm)
600 ml sample collection beaker
100 mm diameter sample collection tray
30° Angle of Repose Standard Correction Cone
Complete original manufacturer's certified folder:
Original manufacturer's Chinese/English operating manual
Factory inspection and design certificate
Installation confirmation file
Operation confirmation document
Instrument Maintenance Log
Certificate of Conformity for Containers and Agitator Components