Pharma Test PTF110-610 Tablet Friability Tester
The Pharma Test PTF 110/210/310/610 series of tablet friability and abrasion testers are designed for pharmaceutical quality control (QC), R&D analysis, and high-throughput testing laboratories. They can be used to quickly assess the mechanical strength, friability, and surface abrasion resistance of uncoated tablets during production, packaging, and transportation. This instrument fully complies with international regulations and standards such as the United States Pharmacopeia (USP) <1216>, the European Pharmacopoeia (EP) <2.9.7>, the Japanese Pharmacopoeia (JP), and the British Pharmacopoeia (BP).
I. Offers a variety of flexible configurations from 1 slot (PTF 110), 2 slots (PTF 210), 3 slots (PTF 310) to 6 slots (PTF 610), supporting simultaneous testing of multiple batches of samples and significantly improving the efficiency of high-throughput quality control.
II. The entire series comes standard with a transparent antistatic Roche friability drum (with an optional flexible Rusch abrasion drum), featuring automatic sample ejection and a standard 10° tilt test stand, accurately meeting the pharmacopoeia testing requirements for large-size and special-shaped tablets.
III. It adopts a high-precision DC brushless motor drive, providing dual control modes of "set speed" and "set running time" (speed 20～70 RPM, standard 25.0 ± 1.0 RPM), and can be connected to an external precision balance for automatic weight reading and real-time calculation of friability (%).
IV. Equipped with a color touch screen interface, built-in method editing and storage, multi-level user permission control and full audit trail functions, fully compliant with GMP and 21 CFR Part 11 data integrity regulations.
Equipment Introduction
New Modular Multi-Drum Configurations
Meets diverse throughput requirements : Offers flexible configurations from 1 slot (PTF 110), 2 slots (PTF 210), 3 slots (PTF 310) to 6 slots (PTF 610), supporting simultaneous testing of multiple batches of samples.
New compact and modern chassis : The entire machine is made of robust and corrosion-resistant materials and has an optimized space ratio design, which can be adapted to the limited table space of various quality control (QC) and R&D laboratories.
Full Pharmacopeia Compliance & Dual Drum Types
Strictly compliant with the pharmacopoeias of various countries : fully compliant with the standards of USP <1216>, EP <2.9.7>, JP and BP for tablet friability and abrasion resistance testing.
Roche and Rusch drums are interchangeable : the standard configuration includes an antistatic transparent Roche friability drum (300 mm in diameter with patented sample guide vanes) and can be quickly replaced with a Rusch abrasion drum to evaluate the abrasion resistance of special particles or coated tablets.
Intelligent Tablet Discharge and 10° Tilt Mechanism
Automatic sampling and non-destructive collection : After the test is completed, the drum automatically reverses, smoothly distributing the tablets into the collection tray, avoiding secondary physical damage caused by manual sampling.
10° Inclination Patent Mechanism : A standard 10° inclination bracket is built into the bottom of the device to precisely solve the problem of rolling stagnation of large or special-shaped tablets during testing.
High-precision brushless motor with dual operating modes.
Precise and vibration-free drive control : Adopts industrial-grade DC brushless motor with a speed range of 20～70 RPM (standard setting 25.0 ± 1.0 RPM), operates quietly and without toner contamination.
Dual control modes for rotation speed and time : Supports setting a fixed number of rotations (e.g., standard 100 rpm) or setting the running time (up to 99 hours and 59 minutes), providing maximum experimental flexibility.
Automated Balance Interface & Friability Calculation
Automatic weight reading and calculation : An external analytical balance can be directly connected via the interface to automatically read the sample weight before/after the test and calculate the friability (% Friability) in real time.
Eliminate errors from manual transcription : Fully automated data transmission and calculation completely eliminate human bias that may arise from manual recording and calculation.
Smart Touchscreen & 21 CFR Part 11 Compliance
Intuitive color touch interface : Built-in modern color touch screen, supporting quick setup, storage and one-click retrieval of multiple test methods.
Regulatory-grade data integrity : Built-in multi-level user management and complete audit trail, supporting data export and printing, fully compliant with GMP and 21 CFR Part 11 requirements.
Product Features
Equipped with high-precision sensors, it accurately assesses the fragility of the tablets.
10° tilt angle expansion accessory
Automatic wear rate calculation mechanism
Overall Specifications
Product Models : PTF 110 / PTF 210 / PTF 310 / PTF 610
Manufacturer : Pharma Test, Germany
Version Specification : Version 1.0E
Product positioning and operating principles :
A fully automated friability and abrasion resistance tester specifically designed for testing the mechanical strength of uncoated tablets and tablet cores.
Evaluate the weight loss of tablets due to friction and impact during coating, transportation and packaging.
The inside of the drum has an arc-shaped baffle that extends to the outer wall, causing the sample to repeatedly tumble and fall during rotation.
After the test is completed, the drum automatically reverses, and the sample is discharged from the outlet into the magnetic collection box.
International Pharmacopoeia and regulatory compliance :
Fully compliant with the friability testing standards of the United States Pharmacopeia, European Pharmacopeia, Japanese Pharmacopeia, and German Pharmacopeia.
The fuselage structure and wear-resistant design fully comply with the requirements of Good Laboratory Standards and Good Pharmaceutical Manufacturing Standards.
Test modes and roller drive specifications :
Drum speed range: 15 to 100 rpm
Speed control accuracy: ±1 rpm
Rotation speed setting: A fixed speed of 25 rpm can be set, or the speed can be customized according to the method.
Rotational revolutions setting range: 2 to 9999 revolutions
Test time setting range: 2 to 9999 seconds
Dual test mode switching: supports setting either the number of rotations or the test time.
Roller mechanism and automatic discharge system :
Standard configuration includes a high-transmittance acrylic standard brittleness roller with an independent, removable top cover.
It features a lidless inlet and outlet, allowing for direct sample loading from the outside or deep internal cleaning.
Magnetic transparent acrylic sample collection slot automatically collects samples after testing and allows for quick and easy removal for cleaning.
Each set of rollers comes with original manufacturer's conformity documentation, which complies with the United States Pharmacopeia and the European Pharmacopeia.
Balance connection and automatic weight reduction calculation :
Supports automatic transfer of sample weights before and after testing using an external analytical balance.
The system automatically compares and calculates the absolute weight loss value with the relative weight loss percentage.
The judgment result is automatically compared with the set upper limit value and the judgment status is marked.
User management and method storage :
The built-in memory can store up to 256 test methods.
Supports up to 32 user accounts and hierarchical access control.
Username and password login authentication protection
Offers a quick, login-free testing feature for easy routine and simple tests.
Operation and display interface :
The color-changing backlit LCD screen uses green, yellow, and red colors to instantly identify the device's operating status.
The rotary knob, combined with function shortcut keys, makes menu navigation intuitive and smooth.
Data storage, output, and communication interfaces :
Built-in integrated thermal printer for real-time printing of test data, statistical results, and calibration reports.
Equipped with a universal serial number port for the host and device, it supports exporting spreadsheet and text reports from USB flash drives.
Supports fast firmware upgrades and factory resets via USB flash drive without a computer.
Equipped with serial communication ports to support connection to external analytical balances, external printers, or laboratory information management systems.
Supports smart network adapters, enabling remote printing and data transmission over local area networks.
Calibration and validation functions :
Built-in dedicated speed and timing software guidance and calibration program
Programmable and effective periodic reminder function, automatically prompting for correction when the time arrives.
The system automatically performs a self-test upon startup to ensure that all components are in a ready state.
Model configuration specifications :
Single-roller model: 1 set of rollers (configured on the right side only)
Double-drum model: 2 sets of drums (1 set on the right and 1 set on the left)
Three-roller model: 3 sets of rollers (single configuration on the right side)
Six-roller model: 6 sets of rollers (3 sets on the right and 3 sets on the left)
Optional accessories and special components :
Antistatic coating brittleness roller: Prevents dust adsorption, significantly improving post-test cleaning efficiency.
Louvered abrasion resistance roller: Specifically designed to evaluate the abrasion resistance limit of samples by continuously applying stress through the blades.
10-degree tilting support: Specifically designed for tablets weighing more than 650 mg, with large diameters, or with special geometric shapes, to prevent sample stacking and falling.
Smart Network Adapter: Supports dual-channel instrument connections to local area networks
External ticket printer
Airframe specifications and power requirements :
Body structure: Hairline stainless steel body
Power requirements: 100-240 volts, 50/60 hertz
External dimensions:
Single drum model: Approximately 39 × 42 × 42 cm (width × depth × height)
Double drum machine model: Approximately 42 × 42 × 42 cm (width × depth × height)
Three-roller model: Approximately 51 × 42 × 42 cm (width × depth × height)
Six-roller model: Approximately 75 × 42 × 42 cm (width × depth × height)
Packaging dimensions:
Single drum model: Approximately 60 × 60 × 79 cm (width × depth × height)
Double drum model: Approximately 60 × 60 × 79 cm (width × depth × height)
Three-roller model: Approximately 60 × 60 × 79 cm (width × depth × height)
Six-roller model: Approximately 80 × 60 × 74 cm (width × depth × height)
Instrument weight:
Single-drum model: Net weight approximately 16.5 kg, gross weight approximately 26.5 kg
Double-drum model: Net weight approximately 18.0 kg, gross weight approximately 28.0 kg
Three-drum model: Net weight approximately 19.5 kg, gross weight approximately 30.0 kg
Six-drum model: Net weight approximately 28.0 kg, gross weight approximately 52.0 kg
Validation and Certification :
All contact parts fully comply with the requirements of the United States Pharmacopeia and the European Pharmacopeia.
Possesses complete electromagnetic compatibility and safety certifications
Standard configuration includes complete original manufacturer installation and operation verification documentation, conformity certificate, and instrument history logbook.