Pharma Test PT-TD300 Tap Density Tester
The Pharma Test PT-TD300 Tapped Density Tester is specifically designed for pharmaceutical formulation development, quality control (QC), and powder manufacturing process characterization. It can be used to determine the tapped volume, tapped density, Hausner ratio, and Carr's Compressibility Index of raw materials before compression into powders, granules, and tablets. This instrument fully complies with international regulations and standards such as the United States Pharmacopeia (USP) <616> (Method 1 and Method 2), the European Pharmacopoeia (EP) <2.9.34>, the Japanese Pharmacopoeia (JP) <3.01>, ASTM B527, and ISO 3953.
I. Offers flexible single-station and dual-station testing platform configurations, fully compatible with the standard pharmacopoeia testing requirements of USP Method 1 (impact stroke 14.0 ± 2.0 mm, frequency 300 times/minute) and USP Method 2 (impact stroke 3.0 ± 0.2 mm, frequency 250 times/minute).
II. Supports various standard graduated cylinders of 10 mL, 25 mL, 50 mL, 100 mL and 250 mL, and adopts a low-noise and stable rotary tapping mechanism design to ensure that the sample powder surface is flat during the tapping process, and maximize the accuracy of volume reading.
III. It adopts an intuitive color touch screen interface, supports custom preset tap counts and continuous test cycles, and can automatically calculate and output key flow indicators such as tap density, Hausner ratio and Carr compression index.
IV. Equipped with multi-level user password permission control, method editing and storage, and complete, immutable audit trail functionality, fully compliant with GMP, GLP, and 21 CFR Part 11 Data Integrity regulations.
Equipment Introduction
Multinational pharmacopoeia standards and dual-method support.
Fully compliant with pharmacopoeias of various countries : fully compliant with international standards and specifications such as USP <616> (Method 1 and Method 2), EP <2.9.34>, JP <3.01>, ASTM B527 and ISO 3953.
Standard dual test method compatibility : Compatible with both USP Method 1 (impact travel 14.0 ± 2.0 mm, frequency 300 times/minute) and USP Method 2 (impact travel 3.0 ± 0.2 mm, frequency 250 times/minute) test requirements.
Flexible Station Layout & Smooth Rotation Mechanism
Flexible configuration of single and dual workstations : Offers a choice of single or dual test workstation models. Dual workstations support two sets of tests to run independently or synchronously, doubling the throughput of quality control.
Automatic and stable sample rotation mechanism : The measuring cylinder rotates smoothly and coaxially during the tapping process, ensuring that the powder surface (Meniscus) is flat and unbiased, maximizing the accuracy and repeatability of volume reading.
Versatile Cylinders & Quick-Lock Clamping
Multi-volume standard graduated cylinder support : Supports various specifications of standard glass graduated cylinders such as 10 mL, 25 mL, 50 mL, 100 mL and 250 mL to meet the needs of testing from micro to large quantities of samples.
Tool-free quick-locking clamp : Ergonomic clamping mechanism ensures that the measuring cylinder remains stable and does not shift under high-speed impact, and can be quickly disassembled and cleaned.
Automated Calculation & Flowability Assessment of Smart Mobility Indicators
Automated physical index calculation : After inputting the sample weight and volume, the system automatically calculates the tapped density, Hausner ratio, and Carr's index.
Real-time assessment of powder flow class : Built-in pharmacopoeia flow classification standards to help R&D and quality control personnel determine the tableting and filling characteristics of powders and granules in real time.
Intuitive Touchscreen & Low-Noise Drive System
Modern color touchscreen : Intuitive graphical interface, supporting preset tap counts, multi-stage loop tap tests, and quick storage and one-click retrieval of test methods.
Noise-reducing and vibration-damping motor transmission mechanism : The precision mechanical transmission structure and silent vibration-damping base design ensure smooth and quiet operation, meeting the comfort requirements of the laboratory environment.
Compliance with Laws and Regulations and Data Integrity Management (Data Integrity & 21 CFR Part 11 Compliance)
Multi-level user access control : Built-in multi-level password security management and operation permission allocation to strictly prevent unauthorized modification of test parameters.
Unalterable audit trail : It has complete audit trail records, supports data export and direct printing from external printers, and fully complies with GMP, GLP and 21 CFR Part 11 requirements.
Product Features
Dual pharmacopoeia method switching; automatic position detection.
Automatic calculation of Hausner ratio and Carr compression index.
Built-in thermal printer
Complete calibration reminder
Overall Specifications
Product Model : PT-TD300
Manufacturer : Pharma Test Apparatebau AG (Germany)
Version Specification : Version 2.0E
Product positioning and operating principles :
It is designed specifically for measuring the apparent density and tapped density of powders, granules, pigments and related solid materials.
It fully complies with the latest editions of the United States Pharmacopeia (USP) <616> Acts I and II, the European Pharmacopoeia (EP) <2.9.34>, DIN EN ISO 787-11, ASTM B527, and ASTM D7481.18 standards.
The single test station integrates a dual measuring cylinder positioning slot. The instrument has an intelligent automatic sensing mechanism that can automatically detect whether the measuring cylinder is placed correctly according to the test method selected by the user.
After the test is completed, the system automatically and accurately calculates the drop density, Hausner ratio, and Carr index, and immediately outputs a complete data report through the built-in printer.
Physical property analysis and flowability assessment :
It supports the measurement of the free settling volume (V0) and the volume after shaking (V1, V2, V3, Vf) of the sample, and automatically evaluates the powder settling ability.
Liquidity is automatically rated based on the Hausner-Nabi and Carr index (Excellent > Good > Fair > Acceptable > Poor > Very Poor > Extremely Poor).
Measuring cylinder specifications and optional accessories :
Standard package includes: 250 ml graduated glass cylinder and dedicated adapter base.
Optional accessories: 250 ml graduated plastic graduated cylinder, and 100 ml, 50 ml, 25 ml, and 10 ml glass graduated cylinders and dedicated adapter kits.
Shaking mechanism and technical parameters :
Number of test stations: Single test station (equipped with Method 1 and Method 2 dual measuring cylinder positioning seats and automatic position sensing).
Cam mechanism: Double cam shaft precision drive, providing two methods for standard stroke height and impact frequency.
Method 1 Specifications:
Stroke height: 14.0 ± 2.0 mm
Shaking frequency: 300 ± 5 times/minute
Method 2 Specifications:
Stroke height: 3.0 ± 0.1 mm
Shaking frequency: 250 ± 5 times/minute
Shaking frequency setting: Supports three-stage programmable settings, with each stage adjustable from 1 to 9999 shakes.
User interface and software management :
The high-contrast color backlit LCD screen uses red, green, and yellow three-color status backlighting to indicate the operation status at a glance.
The rotary knob, combined with function shortcut keys, makes menu navigation intuitive and fast.
Method management: The host can store up to 256 test methods.
User access control: Up to 32 user accounts can be created, supporting multi-level access control (administrator, operator, calibration technician), with account and password login protection; it also provides a quick test function without login.
Data access and updates: Supports standard USB flash drive access to CSV format, exporting text file test reports, and allows direct firmware updates and factory settings restoration via flash drive.
Calibration, self-testing, and effectiveness management :
It has a built-in dedicated digital calibration guide program that covers the number of drops, drop height, drop frequency, balance weight reading, and timer functions.
After the calibration guidance steps are completed, the calibration report will be automatically printed and saved on the host.
It features a programmable and effective cycle reminder function, which automatically prompts for correction when the cycle is about to expire.
It features a quick self-test function upon startup to ensure normal operation and can directly print test records.
Data output and communication interface :
Built-in thermal report printer saves laboratory desktop space.
Balance connection port: RS-232 interface (can be connected to an external balance to automatically transfer sample weight, and also supports manual input).
USB Type-A host interface, USB Type-B device interface, LAN port, RS-232 printer port.
A complete report includes: the inspection department, instrument serial number, firmware version, test date and time, user name, product name, batch number, stroke height, number of drops at each stage, initial volume, sample weight, volume after drop, initial density, drop density, Hausner ratio, Calorie index, evaluation results, and personnel signature.
Mechanism specifications and electrical requirements :
Shell material: Polished stainless steel body with impact-resistant plastic frame.
Power requirements: 110 / 230 V, 50 / 60 Hz.
Instrument dimensions: approximately 50 × 50 × 45 cm (width × depth × height).
Packaging and shipping dimensions: approximately 60 × 60 × 50 cm (width × depth × height).
Instrument net weight / gross weight: approximately 20 kg / 25 kg.
Standard Scope of Supply :
PT-TD300 host (including built-in printer)
250 ml graduated glass cylinder and dedicated adapter
Complete original manufacturer's certified folder:
Operation Manual
Design and factory inspection certificate
Installation confirmation file
Operation confirmation document
Instrument Maintenance Log
Container conformity certificate
Optional accessories :
Specialized soundproof and noise-reducing cover (part number 491-2100)
250 ml graduated plastic graduated cylinder (part number 490-0491)
100 ml graduated glass graduated cylinder and adapter kit (part number 490-0210)
50 ml graduated glass graduated cylinder and adapter kit (part number 491-0350)
25 ml graduated glass graduated cylinder and adapter kit (part number 491-0325)
10 ml graduated glass graduated cylinder and adapter kit (part number 491-0310)