dissoSHIELD® (a brand under Merel Instruments in Slovenia) is a universal, all-in-one light-shielding shield designed for drug dissolution testing, dissolution monitoring of light-sensitive APIs/formulations, long-release testing, and laboratory environmental control. The device integrates high-specification UV-resistant and optical shielding materials, a highly efficient thermal insulation structure, and a universal quick-installation design, providing comprehensive light protection, evaporation prevention, temperature stability, and dust protection in a non-invasive, ready-to-use, and highly compatible manner.

I. All-round photosensitive light protection with excellent UV and full-spectrum visible light blocking performance, allowing direct testing of photosensitive agents without the need to replace the expensive brown dissolution cup, preventing sample photodegradation.

II. Ultimate thermal insulation and temperature control, effectively isolating the laboratory air conditioning outlet and airflow disturbances, maintaining a precise constant temperature of 37.0 ± 0.5 °C, significantly reducing solvent evaporation in long-term sustained-release tests of more than 24 hours.

III. Cleanliness, Dust Prevention, and Environmental Safety Protection: Physically blocks airborne particles and dust from falling into the cup and contaminating the sample, while preventing the escape of organic/volatile solvent gases, thus improving the safety of the laboratory operating environment.

IV. Cross-brand compatibility and quick-installation modular lightweight architecture, tool-free intuitive installation, perfectly compatible with mainstream brand dissolution apparatuses on the market.

Equipment Introduction

• Comprehensive light shielding and photostability protection for photosensitive drugs.

  • Highly effective UV and visible light blocking: Utilizing high-specification optical shielding and anti-light materials, it can completely block ultraviolet (UV) rays and the full spectrum of visible light in the environment, completely preventing photodegradation of light-sensitive active pharmaceutical ingredients (light-Sensitive APIs / OSD Formulations) during the dissolution process, which can last from several hours to tens of hours.

  • Eliminate the risk of amber dissolution vessel deviation: There is no need to replace expensive and unevenly thick amber vessels. Standard transparent dissolution vessels can be used directly for light-proof tests, completely avoiding the interference of amber glass wall thickness tolerance on heat transfer uniformity.

• Ultimate thermal insulation and solvent evaporation protection performance.

  • Maintain a stable temperature of 37.0°C ± 0.5°C: Creates an excellent thermal insulation microenvironment, effectively blocking the disturbance of hot and cold air currents generated by the laboratory air conditioning vents, ventilation system, and personnel movement, ensuring that the temperature at all points inside the cup is uniform and stable.

  • Significantly reduces evaporation loss in long-term tests: For dissolution tests of long-term sustained-release formulations (SR/CR/MR) for 12 hours, 24 hours, or even several days, it can greatly suppress solvent evaporation loss and eliminate concentration measurement distortion and OOS/OOT risks caused by evaporation concentration.

• Cleanliness, dust prevention, and laboratory safety.

  • Prevents contamination from falling dust particles: Provides a robust physical barrier to effectively prevent suspended particles, falling dust, and external impurities from falling into the dissolution vessel, ensuring sample purity and reproducibility of analytical data.

  • Suppressing the escape of volatile gases: Effectively limits the diffusion of volatile gases such as those from special solvents, acidic media, or those containing surfactants, protecting operator health (EHS) and optimizing the laboratory working environment.

• Universal compatibility and modular quick-mount design across brands.

  • Compatible with mainstream brands: Modular universal size design, no need to modify any instrument structure.

  • Intuitive lightweight installation: The structure is lightweight and durable, and can be quickly snapped on and off without tools, without affecting the manual/automatic sampling needle lifting, drug administration and daily cleaning and maintenance flow.

• Pharmaceutical-grade chemical resistance materials and pharmacopoeia compliance.

  • High-quality weather-resistant and corrosion-resistant materials: Made of medical-grade lightweight materials that are resistant to chemical corrosion, acids and alkalis and cleaning agents, it is not easily deformed or deteriorated and is easy to clean and disinfect, fully complying with cGMP and GLP standards.

  • Fully compliant with the pharmacopoeia requirements of various countries: strictly adhering to the strict tolerance (37.0 ± 0.5 °C) for dissolution test temperature and sample stability requirements of USP <711>, EP <2.9.3>, JP and ChP.