The Pharma Test / Pharmag P-DG Dry Granulator Attachment (Part No. 40-01110) is designed for pharmaceutical formulation research and development (R&D), dosage form laboratories (Galenical Labs), and pilot plants. This module connects directly to the P-UAM universal motor drive unit or P-UGD universal gearbox via a standard quick-release flange. It is specifically designed for crushing, extruding, and uniformly granulating post-compression agglomerated materials, tablet fragments (slugs), and dry powders, providing highly reproducible particle size distribution (PSD). It fully complies with the stringent requirements of cGMP, FDA, and the International Pharmacopoeia for pretreatment of solid dosage forms and pre-filling processes for tablets/capsules.

I. Standardized Quick-Lock Attachment Flange: Utilizing industry-standard mounting flanges, it allows for quick installation and removal from the P-UAM/P-UGD drive system within seconds without the need for complex tools, significantly reducing equipment purchase costs and laboratory workspace.

II. High-Efficiency Dry Granulation & Uniform PSD: Featuring a high-torque extrusion rotor structure, it can gently and efficiently extrude and screen pre-compressed plates, large slugs, and agglomerated powders, significantly reducing the generation rate of fine powder and ensuring particle flowability and subsequent tablet quality.

III. Modular Multi-Aperture Screen and Tool-Free Disassembly: Offers precision-cut stainless steel screens in various aperture specifications (e.g., 0.5 mm to 3.0 mm). The entire machine features a quick-release latch structure, allowing for the removal and replacement of the rotor and screen in seconds without the need for additional hand tools.

IV. Pharmaceutical-grade hygienic design and cGMP cleaning verification: All parts in contact with materials are made of high-specification AISI 316/316L stainless steel with a mirror-polished surface (Ra < 0.8 µm), eliminating dead corners and facilitating thorough cleaning and sterilization. It fully complies with cGMP, GLP and FDA cleaning effectiveness standards.

Equipment Introduction

• Bi-Directional Crushing & Precision Dry Granulation Technology

  • Dual-Action Crushing Mechanism: This innovative mechanism employs a dual-direction operating principle—inward crushing of large-volume materials and slugs, followed by outward granulation and shaping of the material through precision breaking combs, effectively preventing material blockage.

  • Highly uniform particle size distribution and low fines: Through adjustable precision rollers and comb tooth structure, particle size can be precisely controlled, greatly reducing excess fines generated by over-grinding, ensuring excellent flowability and compression molding properties in subsequent tablet pressing or filling processes.

• Wide speed range and high-throughput pilot production capacity

  • Flexible and precisely adjustable speed (50 – 450 RPM Variable Speed): With a wide roller speed range of 50 to 450 RPM, operators can flexibly set the optimal speed and shear force according to the brittleness, hardness and target particle size of the material.

  • Pilot-scale high-capacity design (Pilot Scale Output up to 20 kg/h): Compact in size yet possessing a dry grinding and granulation capacity of up to 20 kg/h, it can seamlessly connect laboratory formulation development (R&D), pilot plant formulation, and small-scale mass production needs.

• Industry-standard quick-lock flange and modular suite

  • Tool-Free Quick-Lock Flange Mounting: Adopting an industry-standard flange interface, modules can be installed, locked, and disassembled by hand without tools within seconds, greatly improving the efficiency of multi-module switching in the laboratory.

  • Integrated Modular Process Suite Compatibility: As one of the core modules of Pharmag’s pilot unit operating equipment, it needs to be driven by the P-UAM universal power unit (or P-UGD gearbox), which greatly saves equipment purchase costs and laboratory space.

• Extensive Feed Characteristics & Cross-Industry Applications

  • Wide feed range of solids: Designed for dry crushing and granulation of solids, it can efficiently handle subsequent crushing and granulation processes of pellets, slugs, tablets and various tablets.

  • Multi-Industry Versatility: Widely applicable to various powder engineering fields such as pharmaceuticals, traditional Chinese medicine and natural drugs, fine chemicals, food and health food, agricultural biotechnology, cement and ceramics, cosmetics, detergents and paints.

• cGMP Sanitary Design & Maximum Operational Safety

  • Standard Protective Grid Guard with High Safety: The feed hopper comes standard with a factory-installed protective grid, which ensures smooth material feeding while completely preventing operators from accidentally touching the rotating mechanism, thus ensuring the safety of both personnel and machines.

  • Pharma-grade Stainless Steel Construction: The body is made of high-quality corrosion-resistant AISI 316 / AISI 304 stainless steel, with a smooth surface without dead corners, easy to disassemble and clean, and resistant to various organic solvents and disinfectant alcohol wipes, fully complying with cGMP and GLP cleaning effectiveness standards.